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[目的]观察术菟安胎方联合黄体酮治疗早期先兆流产疗效。[方法]使用随机平行对照方法,将92例门诊患者按就诊顺序编号简单随机分为两组。对照组46例黄体酮20mg/次,1次/d,肌注。治疗组46例术菟安胎方(白术15g,菟丝子30g,川断15g,桑寄生20g,阿胶~(烊化)、黑杜仲各15g,黄芪30g;出血较多加艾叶炭12g,龙骨~煅、牡蛎~煅各20g;纳差乏力,面色无华加党参30g,山药18g;腹部下坠加升麻12g,柴胡6g;恶心呕吐加砂仁~(后下)5g,苏梗6g,陈皮10g;有热加槐花、侧柏炭、黄芩各10g;便秘加麻子仁10g、肉苁蓉15g;伴有感染加金银花15g,知母10g,蒲公英20g;精神紧张加枣仁~炒20g,远志10g),水煎400mL,早晚温服;黄体酮治疗同对照组。连续治疗7d为1疗程。观测临床症状、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组痊愈28例,有效16例,无效2例,总有效率95.65%;对照组痊愈22例,有效18例,无效6例,总有效率86.96%;治疗组疗效优于对照组(P<0.05)。[结论]术菟安胎方联合黄体酮治疗早期先兆流产,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the effect of surgery and tocolysis combined with progesterone on early threatened abortion. [Methods] Using randomized parallel control method, 92 outpatients were randomly divided into two groups according to the sequence numbers of their visits. Control group, 46 cases of progesterone 20mg / time, 1 / d, intramuscular injection. In the treatment group, 46 cases were treated with Atractylodes rhizome (Atractylodes 15g, Dodder seed 30g, Chuanxuan 15g, Sang parasitic 20g, donkey-hide gelatin, black eucommia 15g, Astragalus 30g; Oyster ~ calcined 20g; Nanasia fatigue, non-Chinese face plus Codonopsis 30g, yam 18g; abdomen plus plus cohosh 12g, Bupleurum 6g; nausea and vomiting plus Amomum ~ (after the next) 5g, Stems 6g, dried tangerine peel 10g; Heat plus acacia flower, Arborvitae, skullcap the 10g; constipation plus pockmarked 10g, Cistanche 15g; accompanied by infection plus honeysuckle 15g, Anemarrhena 10g, dandelion 20g; nervous and Zaoren ~ fried 20g, Polygala 10g), water Fried 400mL, morning and evening warm clothes; progesterone treatment with the control group. Continuous treatment 7d for a course of treatment. Observed clinical symptoms, adverse reactions. Continuous treatment of 3 courses to determine the efficacy. [Results] 28 cases were cured, 16 cases were effective, 2 cases were ineffective and the total effective rate was 95.65%. In the control group, 22 cases were cured, 18 cases were effective, 6 cases were ineffective and the total effective rate was 86.96%. The curative effect of the treatment group was better than that of the control group (P <0.05). [Conclusion] The operation Tuan an decoction combined with progesterone treatment of early threatened abortion, with satisfactory results, no serious adverse reactions, it is worth promoting.