目的：探讨应激免疫抑制蛋白对大鼠动脉血压的作用。方法：将部分纯化的应激免疫抑制蛋白作静脉注射，ＭａｃＬａｂ记录仪记录血压。结果：足背静脉注射部分纯化的应激免疫抑制蛋白２００、４００和８００μｇ后，血压下降，并呈明显的量效关系。结论：应激免疫抑制蛋白可明显降低正常大鼠动脉血压，而心率无明显改变 Objective: To investigate the effect of stress immunosuppressive protein on arterial blood pressure in rats. Methods: Partially purified stress immunosuppressive protein was injected intravenously and blood was recorded by MacLab recorder. Results: The blood pressure decreased after 200, 400 and 800 μg of partially purified immunosuppressive proteins were injected into the dorsalis pedis. There was a significant dose-response relationship. Conclusion: The stress immunosuppressive protein can significantly reduce the normal rat arterial blood pressure, but no significant change in heart rate