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胰十二指肠切除术由于其解剖复杂、毗邻重要大血管、手术风险较大，为普通外科疑难手术之一，也是微创外科领域最难攻克的堡垒。对于开展微创胰十二指肠切除术，外科医生丰富的手术经验和精湛的手术操作技巧是手术成功的关键。笔者综述微创胰十二指肠切除术的相关进展，以期进一步明确微创胰十二指肠切除术治疗带来的利益与弊端，从而进一步提高该种手术的质量。“,”Due to the complex anatomy and being adjacent to important large vessels, pancreaticoduodenectomy (PD) is a diffcult procedure with high risk in the ifeld of general surgery, and is also considered the toughest nut to crack in the ifeld of minimal invasive surgery. For carrying out minimally invasive PD, the surgeons’ considerable experience and skillful surgical technique are crucial to the successful operation. hTe authors address the progress with regard to minimally invasive PD, so as to clarify the beneifts and drawbacks brought by minimally invasive PD, and thereby to further improve the quality of this procedure.