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[目的]探讨术前放疗、化疗联合热疗治疗直肠癌局部复发的临床效果。[方法]将32例患者随机分成两组,即对照组和实验组,每组16例,对照组采用单纯放疗治疗,实验组采用放疗、化疗联合热疗治疗,在化疗结束后采用手术治疗。治疗结束后比较两组的有效率。[结果]实验组有效率高于对照组,两组比较差异有统计学意义(P﹤0.05);放疗、化疗联合热疗结束后2～3周进行手术治疗,对照组根治性手术少于实验组,姑息性手术高于实验组,两组比较差异有统计学意义(P﹤0.05)。[结论]术前放疗、化疗联合热疗治疗直肠癌局部复发,可以提高治疗效果,利于根治性手术治疗,通过三者之间的协调,提高患者的生存率,改善患者的生活质量,术前放疗、化疗联合热疗是直肠癌局部复发的重要辅助治疗手段。
[Objective] To investigate the clinical effect of preoperative radiotherapy, chemotherapy and hyperthermia in the treatment of local recurrence of rectal cancer. [Method] 32 patients were randomly divided into two groups, control group and experimental group, 16 cases in each group. The control group was treated with radiotherapy alone. The experimental group was treated with radiotherapy combined with chemotherapy and hyperthermia. Surgical treatment was performed after chemotherapy. The effectiveness of the two groups was compared after treatment. [Results] The effective rate of experimental group was higher than that of control group, with significant difference between the two groups (P <0.05). Surgical treatment was performed 2 to 3 weeks after radiotherapy combined with chemotherapy and hyperthermia. Group, palliative surgery was higher than the experimental group, the difference between the two groups was statistically significant (P <0.05). [Conclusion] Preoperative radiotherapy combined with hyperthermia in the treatment of local recurrence of rectal cancer can improve the therapeutic effect, which is beneficial to radical surgery. Through the coordination among the three, the patients’ survival rate is improved and the quality of life of patients is improved. Radiotherapy, chemotherapy combined with hyperthermia is an important adjuvant treatment of local recurrence of rectal cancer.