论文部分内容阅读
紫杉醇(Paclitaxel,PTX,Taxol)是从美国紫杉中分离出来的新双萜烯成份,代表新一类广谱抗肿瘤药物。临床观察显示治疗晚期乳腺癌效果较好。1临床资料1.1一般资料本组共22例,经病理确诊为乳腺癌,有淋巴结转移(腋窝淋巴结多于4个,或有锁骨上淋巴结转移)或有远处器官转移或局部复发者,均为女性,年龄34～67岁,年龄中位数48岁。Kamfsky评分≥60分,周围血象及肝肾功能检查正常,有临床肿瘤客观疗效观察指标者。病理类型均为浸润型癌。按照UICI的TNM标准分期:Ⅲ期10例,Ⅳ期12
Paclitaxel (PTX, Taxol) is a new diterpene isolated from American yew, representing a new class of broad-spectrum anti-tumor drugs. Clinical observations show that the treatment of advanced breast cancer better. 1 Clinical data 1.1 General Information The group of 22 cases, pathologically diagnosed as breast cancer, lymph node metastasis (axillary lymph nodes more than 4, or supraclavicular lymph node metastasis) or distant organ metastasis or local recurrence were Female, age 34-67 years, median age 48 years old. Kamfsky score ≥ 60 points, peripheral blood and liver and kidney function tests were normal, there are clinical indicators of objective tumor curative effect. Pathological types are infiltrating type of cancer. In accordance with the UICI TNM staging: Ⅲ in 10 cases, Ⅳ 12