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目的 :探讨发生于耳鼻咽喉部的原发性神经内分泌癌的的病理、临床特性及治疗方法 ;方法 :喉非典型类癌 1例 ,行会厌切除术 ;鼻咽部非典型类癌 1例 ,行放疗 ;中耳类癌 1例 ,行右中耳探查及乳突根治术 ;右鼻腔小细胞神经内分泌癌 1例 ,行鼻右侧切开肿瘤切除术及放疗。结果 :喉非典型类癌及鼻咽部非典型类癌患者分别于 5年和 1年后死亡 ;中耳类癌患者随访 3年右耳术腔干洁 ;右鼻腔小细胞神经内分泌癌随访 2年未见复发。结论 :发生于耳鼻咽喉部的原发性神经内分泌癌可分为类癌、非典型类癌、小细胞神经内分泌癌。类癌为低度恶性 ,小细胞神经内分泌癌为高度恶性 ,非典型类癌介于二者之间。治疗以手术切除为主。
Objective: To investigate the pathological, clinical characteristics and treatment of primary neuroendocrine carcinoma in otolaryngology. Methods: One case of atypical atypical carcinoid laryngeal carcinoma, one case of epiglottic excision, one case of atypical carcinoid of nasopharynx, Row radiotherapy; middle ear carcinoid in 1 case, right middle ear exploration and mastoidectomy; right nasal small cell neuroendocrine carcinoma in 1 case, right nasal resection of the tumor resection and radiotherapy. Results: The patients with atypical atypical carcinoids of the throat and the atypical carcinoids of the nasopharynx died after 5 years and 1 year respectively. The patients with middle ear carcinoid were followed up for 3 years and the right ear cavity was clean. The right nasal small cell neuroendocrine carcinoma was followed up 2 No recurrence in years. Conclusion: The primary neuroendocrine carcinomas in otolaryngology can be divided into carcinoid, atypical carcinoid and small cell neuroendocrine carcinoma. Carcinoid as low grade malignancy, small cell neuroendocrine cancer is highly malignant, atypical carcinoid between the two. Surgical treatment of the main.