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已知多种生长因子受体、癌基因产物具有酪氨酸激酶活性且该激酶在调控细胞外信号的信息跨膜传递中,控制着细胞的生长、增殖和转化〔1〕。但是,迄今有关PTK对细胞生长、增殖、转化乃至恶变的确切作用,尤其是在造血系统细胞凋亡及白血病发生中的详细作用尚不清楚。本研究?
It is known that various growth factor receptors and oncogene products have tyrosine kinase activity and this kinase controls cell growth, proliferation, and transformation in the transmembrane transmission of information that regulates extracellular signals [1]. However, the exact role of PTK in cell growth, proliferation, transformation, or even malignant transformation so far, and in particular, the detailed role of PTK in hematopoietic cell apoptosis and leukemia development is not known. this research?