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目的了解上海市北蔡镇老年人群体质量指数(BMI)与骨质疏松症(OP)发病的关系,为本地区OP的防治提供参考。方法使用美国GE公司双能X线骨密度仪对274例上海市北蔡镇60~80岁老年人正位腰椎和左股骨近端进行骨密度测定,根据BMI将其分为体质量正常组(18.5~23.9)和超重组(≥24)。让老人回忆25岁时的身高、体质量,计算出25岁时BMI,再按25岁BMI分为低体质量组(<18.5)、体质量正常组(18.5~23.9)和超重组(≥24)。结果25岁时体质量正常组、低体质量组、超重组的老人OP发病率分别为36%、58%、63%,低体质量组和超重组与体质量正常组比较OP发病率差异均有统计学意义(P均<0.05),低体质量组与超重组OP率无显著性差异(P>0.05)。目前体质量正常组和超重组OP率分别为62%、41%(P<0.005)。结论上海市北蔡镇老年人群OP发病率与目前BMI呈负相关;25岁时低体质量和超重可能影响峰值骨量的形成。
Objective To understand the relationship between body mass index (BMI) and osteoporosis (OP) in Beicai town, Shanghai, and to provide reference for the prevention and control of OP in this area. Methods Bone mineral density (BMD) of lumbar vertebra and proximal femur of 274 old Shanghai Beicai town aged from 60 to 80 years were measured by dual energy X-ray absorptiometry (GE), USA. According to BMI, they were divided into normal weight group 18.5 ~ 23.9) and overweight group (≥24). The elderly were remembered for their height and weight at 25 years of age. The BMI at 25 years old was calculated. The 25-year-old BMI was divided into low body weight group (<18.5), normal body weight group (18.5-23.9) and overweight group (≥24 ). Results The incidence of OP in the normal weight group, low body weight group and overweight group was 36%, 58% and 63% respectively at the age of 25 years. The incidences of OP in the low body weight group and the overweight group were significantly higher than those in the normal weight group (P <0.05). There was no significant difference in the OP rate between the low body weight group and the overweight group (P> 0.05). At present, the normal body mass and overweight group OP rates were 62%, 41% (P <0.005). Conclusions The incidence of OP in elderly population in Beicai, Shanghai is negatively correlated with the present BMI. At 25 years old, low body weight and overweight may affect the formation of peak bone mass.