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目的探讨代谢综合征(MS)组分不同组合在内分泌科住院MS患者中的构成比及其临床特征。方法收集2013年4月至2014年3月在中南大学湘雅二医院内分泌科608例住院MS患者的病历资料。计算不同组合MS患者的构成比。比较不同组合患者大血管并发症和微血管并发症的发生情况及影响因素。结果中心性肥胖、血脂异常、高血压共存(组合1)患者13例(2.14%);中心性肥胖、血脂异常、高血糖共存(组合2)患者112例(18.42%);中心性肥胖、高血压、高血糖共存(组合3)患者65例(10.69%);高血糖、高血压、血脂异常共存(组合4)患者76例(12.50%);中心性肥胖、高血糖、高血压、血脂异常共存(组合5)患者342例(56.25%)。组合3、4、5的大血管并发症和微血管并发症患病率差异无统计学意义,但均高于组合1和组合2(P<0.005)。Logistic回归分析显示,年龄、病程、高血压是MS患者发生大血管并发症和微血管并发症的危险因素。此外,血脂异常、高血糖还是其发生微血管并发症的危险因素。结论中心性肥胖、高血糖、高血压、血脂异常共存的MS患者在内分泌科MS住院患者中所占的比例最高。不同组合的MS患者其大血管并发症和微血管并发症患病率不同。年龄、病程和高血压是大血管和微血管并发症的共同危险因素。
Objective To investigate the constitutional ratio and clinical features of different combinations of metabolic syndrome (MS) components in MS patients admitted to Department of Endocrinology. Methods A total of 608 hospitalized patients with MS were collected from Department of Endocrinology, Xiangya Second Hospital, Central South University from April 2013 to March 2014. Calculate the composition ratio of different combinations of MS patients. The incidence and influencing factors of macrovascular complications and microvascular complications in patients with different combinations were compared. Results There were 13 patients (2.14%) with central obesity, dyslipidemia and hypertension (combination 1), 112 patients (18.42%) with central obesity, dyslipidemia and hyperglycemia (combination 2), central obesity with high There were 65 patients (10.69%) with hypertension and hyperglycemia (combination 3), 76 patients (12.50%) with hyperglycemia, hypertension and dyslipidemia coexisting (combination 4), central obesity, hyperglycemia, hypertension, dyslipidemia There were 342 patients (56.25%) coexisting (combination 5). There were no significant differences in the prevalence of macrovascular complication and microvascular complications in combination 3, 4 and 5, but both were higher than combination 1 and combination 2 (P <0.005). Logistic regression analysis showed that age, course of disease and hypertension were the risk factors of macrovascular complications and microvascular complications in MS patients. In addition, dyslipidemia, hyperglycemia or its risk factors for microvascular complications. Conclusion MS patients with coexistence of central obesity, hyperglycemia, hypertension and dyslipidemia have the highest proportion of MS inpatients with endocrinology. MS patients with different combinations of macrovascular complications and microvascular complications prevalence of different. Age, duration of disease and hypertension are common risk factors for macrovascular and microvascular complications.