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目的评价慢性乙型病毒性肝炎临床诊断与病理诊断符合率,以提高临床诊疗水平。方法患者查肝功能,凝血酶原时间;采用1秒钟快速肝穿刺活检术,对肝穿组织进行炎症分级(G)及纤维化分期(S)。结果病毒性肝病临床与病理诊断分级的总体符合率约66.7%;其中以慢性肝炎重度符合率最高,达80.0%;而以慢性肝炎中度的符合率最低,达50%。结论病毒性肝病临床与病理诊断还存在一定的差异。为提高慢性肝病的临床确诊率,应尽可能行肝组织病理学检查。
Objective To evaluate the coincidence rate of clinical diagnosis and pathological diagnosis of chronic hepatitis B in order to improve the clinical diagnosis and treatment. Methods The liver function and prothrombin time of patients were examined. The liver biopsy was performed by 1-second rapid liver biopsy, and the grading (G) and fibrosis stages (S) were performed. Results The overall coincidence rate of clinical and pathological diagnosis of viral liver disease was about 66.7%. The highest coincidence rate of chronic hepatitis was 80.0%, while the lowest coincidence rate of chronic hepatitis was 50%. Conclusion There are some differences between clinical and pathological diagnosis of viral liver disease. To improve the clinical diagnosis of chronic liver disease, liver pathology should be performed as far as possible.