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本文探讨拉米夫定治疗慢性乙型肝炎患者发生YMDD变异的临床意义。结果表明,拉米夫定治疗慢性乙型肝炎患者发生YMDD变异对部份患者肝脏炎症活动和乙型肝炎病毒复制的抑制作用无显著影响。
This article explores the clinical significance of lamivudine treatment of patients with chronic hepatitis B YMDD mutation. The results showed that the YMDD mutation in patients with chronic hepatitis B treated with lamivudine had no significant effect on the inhibition of hepatic inflammatory activity and hepatitis B virus replication in some patients.