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目的:分析桂东地区泌尿系结石的化学成分与发病的相关危险因素,为该地区泌尿系结石的防治提供依据。方法:收集桂东地区2015年1月~2016年10月经泌尿外科手术或体外冲击波碎石的泌尿系结石患者258例为研究组,采用红外光谱法分析其结石的化学成分;另选同期于我院泌尿外科住院的非结石患者160例为对照组,对两组患者的16个相关变量进行单因素分析与多因素Logistic回归分析。结果:在258例结石样本中,含草酸钙的结石最多,检出率高达91.86%;其次为含羟基磷灰石的结石(23.64%)与含尿酸的结石(19.77%)。Logistic回归分析表明日饮水量<1L、喝浓茶≥1次/d、饮酒≥2次/周、常食用动物内脏、精神紧张度高、有家族史是该地区泌尿系结石的独立危险因素。结论:桂东地区泌尿系结石的化学成分以草酸钙结石为主;发病主要受日饮水量少、喜喝浓茶、喜饮酒、常食用动物内脏、精神紧张度高和有家族史等因素的影响。
OBJECTIVE: To analyze the chemical components of urolithiasis in Guidong area and the related risk factors for the prevention and treatment of urolithiasis in this area. Methods: A total of 258 urolithiasis patients who underwent urological surgery or extracorporeal shock wave lithotripsy from January 2015 to October 2016 in Guidong were selected as the study group. The chemical composition of the stones was analyzed by infrared spectroscopy. A total of 160 patients with non-calculi in hospital were enrolled as control group. One-factor analysis and multivariate Logistic regression analysis were used to analyze 16 related variables in two groups. Results: Among the 258 stone samples, the stones containing calcium oxalate were the most with the detection rate as high as 91.86%. The stones with hydroxyapatite (23.64%) and uric acid stones (19.77%) were the second most. Logistic regression analysis showed that daily drinking water <1L, drinking tea ≥ 1 time / d, drinking more than 2 times / week, often eating animal offal, high mental stress, family history is an independent risk factor for urolithiasis in the region. Conclusion: The chemical constituents of urolithiasis in the east of Guidong are calcium oxalate stones. The incidence of urolithiasis is mainly affected by less daily drinking water, hi tea, hi drinking, eating animal internal organs, high mental stress and family history influences.