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目的:评价2种方案治疗皮肤真菌病的临床疗效。方法:将57例患者随机分为A组28例和B组29例。A组给予特比奈芬250mg/d,连服7d;B组给予氟康唑100mg/d,连服7d,A组和B组同时给予外涂1%盐酸特比萘芬乳膏,bid,连用14d。比较停药时和停药2周后的临床疗效。结果:A组和B组在停药时的总有效率分别为89.3%和82.8%,在停药2周后的总有效率分别为100%和93.1%,2组间无显著性差异(P>0.05)。结论:2组方案治疗皮肤浅部真菌病疗效肯定。
OBJECTIVE: To evaluate the clinical efficacy of two regimens in the treatment of dermatophytosis. Methods: Fifty-seven patients were randomly divided into group A (n = 28) and group B (n = 29). Group A was given terbinafine 250mg / d, even for 7d; Group B was given fluconazole 100mg / d, even for 7d, group A and group B were given topical 1% terbinafine hydrochloride cream, bid, 14d. Comparison of withdrawal and withdrawal of 2 weeks after the clinical efficacy. Results: The total effective rates in group A and group B were 89.3% and 82.8%, respectively, and the total effective rates were 100% and 93.1% respectively after two weeks of withdrawal, with no significant difference between the two groups (P > 0.05). Conclusion: The efficacy of 2 groups in the treatment of superficial mycosis of the skin is definite.