目的探讨Ivor-Lewis术和经左胸行食管大部分切除术及主动脉弓上食管胃吻合术治疗食管癌的临床效果。方法食管癌患者共80例,分为观察组和对照组。对照组患者实施Ivor-Lewis术,观察组患者实施经左胸行食管大部分切除术及主动脉弓上食管胃吻合术。观察两组患者术后并发症、5年生存率、5年肿瘤复发率情况。结果观察组中并发症发生率分别和对照组比较,差异无统计学意义(P>0.05)。观察组患者中5年生存患者共15例,观察组5年生存率为37.5%;对照组患者中5年生存共16例,5年生存率为40.0%;观察组患者中5年肿瘤复发30例,5年肿瘤复发率为75.0%;对照组患者中5年肿瘤复发29例,5年肿瘤复发率为72.5%。观察组5年生存率和5年复发率分别和对照组比较,差异无统计学意义(P>0.05)。结论 Ivor-Lewis术和经左胸行食管大部分切除术及主动脉弓上食管胃吻合术治疗食管癌的临床效果近似,可根据患者具体情况选择手术方式。 Objective To investigate the clinical effect of Ivor-Lewis surgery and esophagectomy on the left thoracic esophagus and esophagogastrostomy on the aortic arch. Methods A total of 80 patients with esophageal cancer were divided into observation group and control group. Patients in the control group underwent Ivor-Lewis surgery. The patients in the observation group underwent most of the resection of the left esophagus with esophageal-gastric anastomosis on the aortic arch. The postoperative complications, 5-year survival rate and 5-year tumor recurrence rate were observed in both groups. Results The incidence of complications in the observation group and the control group, respectively, the difference was not statistically significant (P> 0.05). The 5-year survival rate was 37.5% in the observation group, 16 in the 5-year survival rate and 40.0% in the 5-year survival rate in the observation group and 5 years in the observation group. For example, the 5-year tumor recurrence rate was 75.0%. In the control group, 29 patients had 5-year tumor recurrence and 5-year tumor recurrence rate was 72.5%. The 5-year survival rate and 5-year recurrence rate in the observation group were not significantly different from those in the control group (P> 0.05). Conclusions The clinical effect of Ivor-Lewis surgery and esophageal cancer treated with left-thoracic esophageal resection and aortic arch esophagogastrostomy is similar, and the operation mode can be selected according to the specific conditions of patients.