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目的评价培菲康联合福松治疗慢性功能性便秘的临床疗效。方法85例经确诊慢性功能性便秘患者随机分为3组,治疗组(A组)32例,给予口服培菲康420mg/次,每日3次,福松10mg/次,每日2次;对照组分为B组和C组,B组30例,口服培菲康420mg/次,每日3次,C组23例,口服福松10mg/次,每日2次,疗程均为4周。观察症状缓解情况并做对比分析。结果治疗4周后,3组总有效率分别为99.9%,56.7%,73.9%,治疗组与对照组相比较,差异有显著性意义(P分别<0.01和0.05)。结论培菲康联合福松治疗慢性功能性便秘具有明确的临床意义。
Objective To evaluate the clinical efficacy of combination of pefloxacin and fosfoprofen in the treatment of chronic functional constipation. Methods Totally 85 patients with chronic functional constipation were divided into three groups randomly. The treatment group (group A), 32 patients were given Peifei Kang 420mg once daily, Fufang 10mg twice daily, The patients were divided into two groups: group B and group C, group B 30, oral peifendan 420 mg / time 3 times per day, group C 23 and oral fosampus 10 mg / time 2 times daily for 4 weeks. Observe the symptom relief and do comparative analysis. Results After 4 weeks of treatment, the total effective rates of the three groups were 99.9%, 56.7% and 73.9% respectively. There was significant difference between the treatment group and the control group (P <0.01 and 0.05 respectively). Conclusion Pefloxacin combined with fluffy treatment of chronic functional constipation has a clear clinical significance.