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目的研究不同浓度次氯酸钠溶液在根管治疗中作用。方法共选入80个研究对象,随机分为四组:A、B、C和D组,对每组行根管预处理后,依次按1.0%、1.5%、2.0%和2.5%的次氯酸钠浓度冲洗,冲洗时间为1min。以疼痛作为安全性判断标准,而以复诊率作为疗效的判断标准,相对应的时间点依次是24h和1年,然后行统计学分析。结果在以疼痛分级为标准的基础上,四个浓度组之间没有显著的统计学差异(P=0.651);而以复诊作为疗效观察时,2.0%和2.5%浓度的次氯酸钠疗效优于1.0%和1.5%浓度的次氯酸钠疗效,且有显著的统计差异,P=0.003,而且2.0%和2.5%浓度的次氯酸钠两组之间在治疗效果上没有统计学差异,P=0.063。结论2.0%浓度的次氯酸钠溶液在根管治疗中具有很好的安全性和较好的疗效。
Objective To study the effect of different concentrations of sodium hypochlorite solution in root canal therapy. Methods A total of 80 subjects were selected and randomly divided into four groups: A, B, C and D groups. After root canal pretreatment in each group, the sodium hypochlorite concentrations of 1.0%, 1.5%, 2.0% and 2.5% Rinse, wash time of 1min. To pain as a safety criteria, and the referral rate as a criterion for the efficacy of the corresponding time points were followed by 24h and 1 year, and then statistical analysis. Results There was no significant difference between the four concentration groups (P = 0.651) based on the grading of pain. The efficacy of 2.0% and 2.5% sodium hypochlorite was better than 1.0% And 1.5% sodium hypochlorite, with significant statistical difference (P = 0.003). There was no significant difference in the therapeutic effect between the two groups at 2.0% and 2.5% sodium hypochlorite, P = 0.063. Conclusion 2.0% sodium hypochlorite solution has good safety and good curative effect in root canal therapy.