刺激调制下的低频自发振荡信号时空分析

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利用光学功能成像技术研究了刺激条件下SD大鼠体感区低频自发振荡信号的时空规律,发现了左、右脑体感区的低频振荡信号在刺激后具有幅度增强、相位发生改变、趋于同步的现象,并据此讨论了低频自发振荡的产生机理,认为细小动脉的舒缩对绿光((546±10)nm)下皮层中的自发振荡贡献很大.此外,还研究了动脉、静脉与皮层三处的低频振荡信号的相对相位关系,发现红光((605±10)nm)下静脉和皮层的低频振荡信号有明显的相位差别,皮层领先静脉0.6~1.0s;绿光下,动脉、静脉和皮层三处的相位差别不明显,三者基本同步.分析认为,绿光下在血管处采集的振荡信号与皮层处采集的振荡信号的形成机理可能不同. The temporal and spatial regularity of low-frequency spontaneous oscillation signal in somatosensory zone of SD rats was studied by optical functional imaging technique. It was found that the low frequency oscillation signal of somatosensory region of left and right brain had amplitude enhancement and phase change after stimulation, which were in synchronicity The mechanism of spontaneous oscillation at low frequency is discussed in this paper. It is concluded that contraction and contraction of small arteries contribute greatly to the spontaneous oscillation in the cortex of (546 ± 10) nm green light. In addition, arterial, venous and The relative phase relationship of the low-frequency oscillation signals in the three cortices showed that there was a significant phase difference between the low-frequency oscillation signals of the veins and the cortex in the red light ((605 ± 10) nm), with a leading cortex of 0.6 to 1.0 s in the cortex; , And the phase difference between veins and cortices was not obvious and the three were basically synchronous.The analysis suggests that the formation mechanism of the oscillation signal collected in the blood vessel and the oscillation signal collected in the cortex may be different under green light.
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