目的了解广州市学生的艾滋病病毒(HIV)流行特征,为开展对该人群的艾滋病(AIDS)防控工作提供科学依据。方法回顾性分析广州市2002-2012年学生的HIV流行特征。结果 2002-2012年,共报告117例学生HIV感染者/AIDS病例,占广州市总病例的比例从2008年的0.5%上升至2012年的2.5%。平均年龄(22.1±2.9)岁,最小14岁;男性占96.6%;大专及以上占79.5%;病例至少来自47所大中专院校。性传播感染占95.7%(112/117),同性性传播占72.6%(85/117);2009-2012年,学生病例中的同性性传播的比例逐年增加(χ2=6.70,P=0.035),2008-2012年,总体疫情中同性性传播的比例逐年增加(χ2=209.07,P=0.000);2008-2012年,学生中HIV感染者/AIDS病例同性性传播的比例高于广州市同期总体疫情中同性性传播的比例,差异有统计学意义(χ2=136.05,P=0.000)。病例通过自愿咨询检测发现的占32.5%,专题调查占25.6%。2008-2012年,学生人群中AIDS病例发现的时间较总体人群早(χ2=9.07,P=0.003),CD+4T淋巴细胞数>200个/μL占92.3%。结论HIV对学生的影响已逐渐显现,应及早采取针对性的措施降低AIDS对该人群的危害。 Objective To understand the epidemiological characteristics of HIV in Guangzhou and to provide a scientific basis for prevention and control of AIDS in this population. Methods A retrospective analysis of Guangzhou students from 2002-2012 epidemic characteristics of HIV. Results A total of 117 HIV / AIDS cases were reported in 2002-2012, accounting for 2.5% of total cases in Guangzhou from 0.5% in 2008. The average age (22.1 ± 2.9) years old, minimum 14 years old; men 96.6%; college and above accounted for 79.5%; at least 47 cases from colleges and universities. Sexually transmitted infections accounted for 95.7% (112/117) and same-sex sexes accounted for 72.6% (85/117). The proportion of homosexual transmission in student cases increased year by year (χ2 = 6.70, P = 0.035) from 2009 to 2012, From 2008 to 2012, the proportion of homosexual transmission in the overall outbreak increased year by year (χ2 = 209.07, P = 0.000). From 2008 to 2012, the proportion of homosexual transmission of HIV / AIDS cases among students was higher than that of the same period in Guangzhou Proportion of homosexual transmission was statistically significant (χ2 = 136.05, P = 0.000). 32.5% were found through voluntary counseling and testing, and 25.6% were from thematic surveys. In 2008-2012, AIDS cases were found earlier in the student population than in the general population (χ2 = 9.07, P = 0.003), and the number of CD + 4T lymphocytes> 200 / μL accounted for 92.3%. Conclusion The impact of HIV on students has gradually emerged, targeted measures should be taken as soon as possible to reduce the risk of AIDS in this population.