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报道KAL对小鼠实体瘤的抑瘤作用及对腹小型瘤的生存期的作用。结果示KAL对S—180实体瘤生长有比较明显抑制作用,KAL0,5,1,2g/kg,igx9天抑瘤率在41%~60%之间,KAL同前给药对荷S—180腹水型癌小鼠生存期延长率在39%~49%间,对荷Ehrlich腹水型癌(EAC)小鼠生存期延长率在31%~49%之间。本文还报道KAL对正常小鼠、荷瘤小鼠及环磷相酰胺造成迟发性过敏反应(DTH)低下模型小鼠的DTH反应的影响,KAL对以上三种状态下小鼠DTH反应均有增强作用。
The antitumor effect of KAL on solid tumors in mice and the effect on the survival of abdominal small tumors were reported. The results showed that KAL significantly inhibited the growth of solid tumors of S-180, KAL0, 5, 1, 2g/kg, igx9 days tumor inhibition rate between 41% to 60%, KAL pre-administration of Dutch S-180 The survival rate of ascites carcinoma mice was between 39% and 49%, and the survival rate of Ehrlich ascites carcinoma (EAC) mice was between 31% and 49%. This article also reported the effects of KAL on DTH responses in mice with delayed type hypersensitivity (DTH) induced by normal mice, tumor-bearing mice, and cyclophosphamide, and KAL had a response to DTH in mice in all three states. Enhanced effect.