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目的观察干扰素雾化吸入治疗小儿病毒性肺炎的临床效果。方法将84例病毒性肺炎患儿随机分为试验组与对照组各42例。试验组采用α1b干扰素治疗,对照组采用利巴韦林治疗,2组均采用雾化吸入方式,对比2组临床疗效和退热时间及啰音消失时间。结果试验组总有效率为90.48%高于对照组的64.29%,差异有统计学意义(P<0.05)。试验组患儿退热时间、啰音消失时间均短于对照组,差异均有统计学意义(P<0.05)。结论病毒性肺炎患儿采用干扰素治疗的效果显著,安全可靠,值得推广。
Objective To observe the clinical effect of inhalation of interferon on children with viral pneumonia. Methods Eighty-four children with viral pneumonia were randomly divided into experimental group and control group with 42 cases each. The experimental group treated with α1b interferon, the control group treated with ribavirin, two groups were used inhalation mode, the clinical efficacy and antipyretic time and rales disappear time. Results The total effective rate of the experimental group was 90.48% higher than that of the control group (64.29%), the difference was statistically significant (P <0.05). The patients in experimental group had shorter antipyretic time and shorter rales compared with the control group, the difference was statistically significant (P <0.05). Conclusions The effect of interferon treatment in children with viral pneumonia is significant, safe and reliable, and worthy of promotion.