笔者用20％甘露醇抢救颅内压急剧升高的病人时,发现2例病情迅速恶化而死亡。通过46例急性颅内高压症应用甘露醇的临床观察,发现应用20％甘露醇存在先升颅内压而后降颅压的过程。现报告如下。 1 临床资料 46例急性颅内高压症,为我院1988年1月至1996年11月的住院病人。男29例,女17例;年龄15～74岁。原发病:中枢神经系统感染30例,脑血管病6例,脑外伤5例,中毒5例。全组病例经腰穿或脑室引流管测颅压均>26.7kPa。 2 方法 When I used 20% mannitol to rescue patients with a sharp rise in intracranial pressure, I found two cases of rapid deterioration and death. By 46 cases of acute intracranial hypertension clinical observation of mannitol, found that the use of 20% mannitol increased intracranial pressure and then decreased intracranial pressure process. The report is as follows. 1 clinical data 46 cases of acute intracranial hypertension, our hospital January 1988 to November 1996 inpatients. 29 males and 17 females; aged 15 to 74 years old. Primary disease: Central nervous system infection in 30 cases, 6 cases of cerebrovascular disease, brain injury in 5 cases, 5 cases of poisoning. All patients by lumbar puncture or intraventricular drainage tube intracranial pressure were> 26.7kPa. 2 methods