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受体是药物筛选的重要靶标,基于受体的药物高通量筛选是药物筛选的主要类型之一。本文根据受体作用原理,按照检测对象的不同,从直接与间接检测的角度,将基于受体的药物高通量筛选进行了分类,总结了基于受体的几种不同的药物筛选模型,并简要介绍了高通量筛选技术在中药研究中的应用,对药物筛选的发展进行了展望。
Receptors are important targets for drug screening. Receptor-based drug high-throughput screening is one of the major types of drug screening. Based on the principle of receptor, we classify receptor-based high-throughput screening from direct and indirect detection according to the different detection objects, and summarize several different receptor screening-based drug screening models The application of high-throughput screening technology in TCM research is briefly introduced, and the prospect of drug screening is prospected.