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目的:观察制霉菌联合六味地黄丸治疗老年口腔念珠菌病的临床效果。方法:取2012年2月-2014年2月广东省韶关市口腔医院收治的80例老年口腔念珠菌病患者作为研究对象,随机分为对照组与观察组,每组各40例,对照组单纯给予制霉菌素片治疗,观察组同时加用六味地黄丸治疗,观察两组患者治疗后临床症状积分的变化情况,比较其治疗效果。结果:观察组食欲不振症状评分为(0.58±0.40)分,心烦症状评分为(1.05±0.51)分,口干(1.02±0.49)分,口腔黏膜灼痛(0.74±0.43)分,均明显低于对照组,差异有统计学意义(P<0.05);观察组痊愈20例,显效13例,好转5例,总有效率高达95.0%,明显高于对照组的75.0%,组间比较,差异有统计学意义(P<0.05)。结论:在口腔念珠菌感染的老年患者的临床治疗中,采用六味地黄丸联合常规制霉菌素片治疗,可提高患者的治疗效果,改善患者的临床症状。
Objective: To observe the clinical efficacy of mold-making combined with Liuweidihuangwan in the treatment of oral candidiasis in the elderly. Methods: Eighty elderly oral candidiasis patients admitted to Shaoguan Stomatological Hospital of Guangdong Province from February 2012 to February 2014 were randomly divided into control group and observation group, 40 cases in each group. The control group was simple Given nystatin tablets treatment, observation group also added Liu Wei Di Huang Wan treatment, observation of two groups of patients after treatment of clinical symptom score changes, and compare the treatment effect. Results: The score of appetite in observation group was (0.58 ± 0.40) points, the score of apathetic symptoms was (1.05 ± 0.51), dry mouth (1.02 ± 0.49) points and oral mucosal burning pain (0.74 ± 0.43) points were significantly lower In the control group, the difference was statistically significant (P <0.05); the observation group cured 20 cases, markedly effective in 13 cases, improved in 5 cases, the total effective rate as high as 95.0%, significantly higher than the control group 75.0%, between groups, the difference There was statistical significance (P <0.05). Conclusion: In the clinical treatment of elderly patients with oral Candida infection, the combination of Liuweidihuangwan and conventional nystatin tablets can improve the therapeutic effect and improve the clinical symptoms of patients.