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目的 探讨肾移植术后巨细胞病毒 (CMV)肺炎的诊断和治疗。方法 回顾性总结 32例肾移植术后发生CMV肺炎的临床资料 ;通过检测外周血中CMVIgM和 (或 )CMVDNA ,结合临床症状及胸片明确诊断 ;以更昔洛韦治疗 ,同时防治混合感染 ,加强营养支持 ,并根据动脉血氧分压 ,尽早使用呼吸机。结果 2 7例 ( 84 .4 % )治疗有效 ,其中 2 5例治愈 ,2例好转 ;死亡 5例。结论 对肾移植术后CMV肺炎应尽早诊断、及时应用以更昔洛韦为主的综合治疗。
Objective To investigate the diagnosis and treatment of cytomegalovirus (CMV) pneumonia after renal transplantation. Methods The clinical data of 32 patients with CMV pneumonia after renal transplantation were retrospectively reviewed. CMVIgM and / or CMVDNA in peripheral blood were detected and combined with clinical symptoms and chest radiographs for definite diagnosis. Combined with ganciclovir, Strengthen nutritional support and use ventilator as soon as possible based on arterial oxygen pressure. Results Twenty-seven (84.4%) patients were cured, of which 25 were cured, 2 were improved and 5 were fatal. Conclusion CMV pneumonia after renal transplantation should be diagnosed as soon as possible, and timely application of ganciclovir - based comprehensive treatment.