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目的:对奥曲肽注射液治疗急性胰腺炎的有效性和安全性进行调查。方法:选择我院2013年9月-2015年9月间50例急性胰腺炎患者,患者入院后将其随机分为两组,一组为对照组,另一组为观察组,每组25例,对照组患者采用常规治疗,观察组患者同时采用奥曲肽注射液进行治疗,比较两组患者的治疗效果,同时调查患者治疗过程中不良反应发生率。结果:对照组患者治疗效果显著的7例,治疗后病情明显改善的8例,评价有效率为73.0%;对照组患者治疗后效果显著的12例,治疗后病情明显改善的11例,评价有效率为94.6%,两组比较存在明显差异,P<0.05。两组患者治疗过程中均未发生不良反应。结论:奥曲肽注射液在急性胰腺炎患者中的治疗效果非常显著,能够改善患者预后,减轻炎症反应。
Objective: To investigate the efficacy and safety of octreotide injection in the treatment of acute pancreatitis. Methods: Fifty patients with acute pancreatitis in our hospital from September 2013 to September 2015 were selected and randomly divided into two groups: one was control group and the other was observation group, with 25 cases in each group The patients in the control group were treated by routine treatment. The patients in the observation group were treated with octreotide injection at the same time. The treatment effect was compared between the two groups. The incidence of adverse reactions during the treatment was also investigated. Results: In the control group, there were 7 cases with significant therapeutic effect, 8 cases with obviously improved condition after treatment, and the effective rate was 73.0%. In the control group, 12 cases were significantly improved after treatment and 11 cases were significantly improved after treatment Efficiency was 94.6%, there was a significant difference between the two groups, P <0.05. No adverse reactions occurred in both groups during the course of treatment. Conclusion: Therapeutic effect of octreotide injection in patients with acute pancreatitis is very significant, which can improve the prognosis of patients and reduce the inflammatory reaction.