目的探讨原发性腹膜后肿瘤术前介入治疗在减少手术出血量、提高完整切除率和降低手术死亡率中的意义。方法回顾性分析2004-10~2013-12行原发性腹膜后肿瘤手术患者48例,以术前介入治疗+手术12例作为试验组,直接手术36例作为对照组。观察指标包括手术出血量、完整切除率和手术死亡率。结果试验组12例均顺利完成手术,其中完整切除肿瘤10例,无手术死亡病例,术中出血量为(1976.67±273.34)ml。对照组33例顺利完成手术(完整切除肿瘤18例),1例术中死亡,2例术后死亡,术中出血量为(2597.22±801.24)ml。试验组的术中出血量比对照组少(P<0.05),肿瘤完整切除率比对照组的高(P<0.05)。两组手术死亡率比较差异无统计学意义(P>0.05)。结论原发性腹膜后肿瘤术前介入治疗可减少手术出血量,提高完整切除率,对手术死亡率则不具有影响。 Objective To investigate the significance of preoperative interventional treatment of primary retroperitoneal tumor in reducing the amount of surgical bleeding, improving the complete resection rate and reducing the operative mortality rate. Methods Retrospective analysis of 48 cases of primary retroperitoneal tumor surgery in 2004-10 ~ 2013-12, preoperative intervention + surgery in 12 cases as the experimental group and direct surgery in 36 cases as the control group. Observations include surgical bleeding, complete resection and surgical mortality. Results In the experimental group, 12 cases completed the operation successfully. Among them, 10 cases were completely resected without any surgical death and the amount of bleeding during operation was (1976.67 ± 273.34) ml. The control group of 33 patients successfully completed the operation (complete resection of the tumor in 18 cases), 1 case died, 2 patients died after surgery, blood loss was (2597.22 ± 801.24) ml. The bleeding volume of the experimental group was less than that of the control group (P <0.05), and the complete resection rate of the tumor group was higher than that of the control group (P <0.05). There was no significant difference in operative mortality between the two groups (P> 0.05). Conclusion Preoperative interventional treatment of primary retroperitoneal tumor can reduce the amount of surgical bleeding, improve the complete resection rate, but have no effect on the operative mortality.