新生儿消化系统疾病中,疑难性疾病占一定比例,对该类疾病的诊治有时非常棘手。其中,疑难性新生儿黄疸多以高直接胆红素常见,由遗传代谢紊乱导致的胆汁淤积亦不少见;疑难性腹泻国内常见感染性腹泻,近年亦比 Neonatal digestive diseases, difficult diseases account for a certain percentage of the diagnosis and treatment of such diseases is sometimes very tricky. Among them, intractable neonatal jaundice and high direct bilirubin are common, caused by genetic metabolic disorders caused by cholestasis is not uncommon; difficult diarrhea common infectious diarrhea in recent years than