肝纤维化是大多数慢性肝病共有的组织学改变,因此,能否终止肝纤维化的进展甚或逆转至正常,是治疗慢性肝病的关键。在肝纤维化的发病机制及治疗研究中,细胞因子网络始终是人们研究的热点。结缔组织生长因子(connectivetissuegrowthfactorCTGF)是一种新发现的细胞因子,1991年由Br Liver fibrosis is a common histological change in most chronic liver diseases. Therefore, whether or not to terminate or even reverse liver fibrosis is the key to treating chronic liver disease. In the pathogenesis and treatment of liver fibrosis research, cytokine network has always been the focus of research. Connective tissue growth factor (CTGF) is a newly discovered cytokine. In 1991, Br