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目的观察胶原酶盘外溶核术中曲安奈德对糖尿病患者血糖的影响。方法将腰椎间盘突出症经骶裂孔硬膜囊前间隙和椎旁椎间孔行胶原酶盘外溶核术,单纯腰椎间盘突出症患者作为对照组(n=20)与合并糖尿病患者作为观察组(n=20),术中均注入曲安奈德,术前、术后24、48、72 h测定血糖值。结果两组患者组内比较术后24h血糖增高均有统计学意义 (P<0．01),术后48、72 h血糖与术前比较无统计学差异(P>0．05),两组间比较术后24、72 h差异有统计学意义(P<0．05),术后48h无统计学差异(P>0．05)。结论胶原酶盘外溶核术中糖尿病患者可以注入曲安奈德,但血糖必须控制在一定范围内。
Objective To observe the effect of triamcinolone acetonide on the blood glucose in patients with diabetes mellitus with collagenase. Methods The lumbar intervertebral disc herniation by the sacral fissure sac anterior dural space and paravertebral foramen peritoneal cavity solution nucleolus, simple lumbar disc herniation patients as a control group (n = 20) and patients with diabetes as the observation group (n = 20). All patients were injected with triamcinolone acetonide intra-operatively. The blood glucose level was measured 24, 48 and 72 h after operation. Results There was significant difference in blood glucose between the two groups (P <0.01) 24 h after operation and no significant difference between 48 h and 72 h after operation (P> 0.05) The difference between the two groups was statistically significant at 24 and 72 h after operation (P <0.05), but no significant difference at 48 h after operation (P> 0.05). CONCLUSION: Triamcinolone acetonide can be injected into patients with diabetes mellitus during collagenase discoid surgery, but blood glucose must be controlled within a certain range.