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目的 探讨扁桃体癌放射治疗方法、疗效和影响预后的因素。方法 回顾性分析我科1971年 8月至 1995年 10月收治的经病检证实的扁桃体癌 71例 ,外照射 +腔内治疗组 15例 ,单纯外照射组 39例 ,外照射 +化疗组 17例。结果 外照射 +腔内治疗组局部控制率为 82 .1% ,单纯外照射组局部控制率为 6 8.4 % ,外照射 +化疗组局部控制率为 6 4 .2 %。外照射 +腔内治疗组局部控制率与单纯外照射和外照射 +化疗组相比 ,差异有显著性意义 (χ2 =4 .6 5 ,P =0 .0 30 ;χ2 =5 .6 5 ,P =0 .0 18)。外照射 +腔内治疗组 3、5、10年生存率分别为 76 .3%、5 3.2 %和 31.2 % ,单纯外照射组 3、5、10年生存率分别为 74 .0 %、4 5 .2 %和 33.5 % ,外照射 +化疗组 3、5、10年生存率分别为 75 .2 %、4 7.1%和 2 5 .3% ,3个组 3、5、10年生存率相互比较 ,差异均无显著性意义 (P >0 .0 5 )。结论 腔内治疗作为原发灶推量手段 ,能提高局部控制率 ,但不能提高生存率。
Objective To explore the radiotherapy methods of tonsillar carcinoma, the curative effect and the prognostic factors. Methods A retrospective analysis of 71 patients with confirmed tonsil cancer admitted from August 1971 to October 1995 in our department, 15 patients undergoing external beam irradiation + endovascular treatment, 39 patients undergoing external irradiation alone and 17 patients undergoing external irradiation plus chemotherapy example. Results The local control rate was 82.1% in external beam + endovascular group, 6 8.4% in external beam irradiation group and 6.42% in external beam irradiation + chemotherapy group. The difference between the two groups was significant (χ2 = 4.65, P = 0.30; χ2 = 5.56, P <0.01) P = 0 .0 18). The 3-, 5-, 10-year survival rates were 76.3%, 52.2% and 31.2% in the external beam + endovascular group, respectively, and the 3, 5 and 10-year survival rates were 74.0% and 45% .2% and 33.5% respectively. The 3-, 5-, 10-year survival rates were 75.2%, 41.1% and 25.3% respectively in external beam plus chemotherapy group, and the 3-, 5-, 10-year survival rates of the three groups were compared with each other , There was no significant difference (P> 0.05). Conclusion Endovascular treatment as a measure of primary tumor volume, can improve the local control rate, but can not improve the survival rate.