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目的:观察血液灌流联合血液透析治疗尿毒症顽固性皮肤瘙痒的临床疗效。方法:选择维持性血液透析中20例出现皮肤瘙痒的患者为研究对象,在常规透析的基础上给予其血液灌流+血液透析治疗,每周1次。观察治疗前后患者甲状旁腺素(PTH)、钙(Ca)、磷(P)水平及皮肤瘙痒症状改善情况。结果:治疗2个月后,20例患者的皮肤瘙痒症状均有不同程度的改善,其中显效14例(70%),有效5例(25%),无效1例(5%)。结论:血液灌流联合血液透析治疗尿毒症顽固性皮肤瘙痒疗效较好,值得推广应用。
Objective: To observe the clinical efficacy of hemoperfusion and hemodialysis in the treatment of intractable pruritus of uremia. Methods: Twenty patients with pruritus in maintenance hemodialysis were enrolled in this study. Hemoperfusion and hemodialysis were performed on the basis of conventional dialysis once a week. Observed before and after treatment in patients with parathyroid hormone (PTH), calcium (Ca), phosphorus (P) and skin pruritus symptoms improved. Results: After 2 months of treatment, the pruritus symptoms of 20 cases all improved to some extent, of which 14 cases (70%) were markedly effective, 5 (25%) effective and 1 (5%) ineffective. Conclusion: Hemoperfusion combined with hemodialysis treatment of uremic intractable pruritus has a good effect, which is worth popularizing and applying.