作者在用抗体诱发红细胞溶血法律立的红细胞在体衰老模型的基础上，研究了红细胞衰老过程中渗透脆性的变化。结果显示，随着红细胞年龄的增加，其渗透脆性增加。推论其渗透脆性的变化可能与红细胞膜结构及红细胞几何形状（即红细胞表面积与体积之比）的变化有关。 Based on the aging model of erythrocytes induced by antibody-induced erythrocyte hemolysis, the author studied the changes of osmotic fragility during the aging of erythrocytes. The results showed that as the age of erythrocytes increased, the osmotic fragility increased. It is concluded that the change of infiltration fragility may be related to the change of erythrocyte membrane structure and erythrocyte geometry (ie, the ratio of erythrocyte surface area to volume).