目的　探讨 2型糖尿病合并脑梗死危险因素。方法　应用 1∶1配比的病例对照研究方法。应用条件logistic回归模型对资料进行分析。结果　文化程度与 2型糖尿病合并脑梗死有关。患 2型糖尿病以后 ,适当加强体育锻炼和劳动强度较大可以减小脑梗死发生的危险性。高密度脂蛋白 (HDL C)越高 ,2型糖尿病合并脑梗死的危险性越小。血糖控制以后 ,也可以降低 2型糖尿病合并脑梗死的危险性。上述因素为保护性因素。盐摄入过多可增加 2型糖尿病合并脑梗死的危险性。打鼾使 2型糖尿病患者发生脑梗死的危险性增加。高血压是 2型糖尿病合并脑梗死独立的危险因素。房颤是 2型糖尿病合并脑梗死的重要危险因素。A型性格与 2型糖尿病合并脑梗死有关 ,显示 2型糖尿病发生脑梗死有明显的个性特征存在。高胰岛素血症是 2型糖尿病发生脑梗死的危险因素。低密度脂蛋白 (LDL C)、载脂蛋白a [Lp(a) ]、纤维蛋白原 (Fg)水平增高 ,可以增加 2型糖尿病合并脑梗死的危险性。研究未发现吸烟、饮酒、口服避孕药、妊娠中毒症、总胆固醇 (TC)、甘油三酯 (TG)、Apo B与 2型糖尿病合并脑梗死有关。结论　为了控制 2型糖尿病合并脑梗死应提倡适当加强体育锻炼 ,多食蔬菜 ,控制盐的过多摄入 ,控制血糖和血压以及高胰岛素血症 Objective To investigate the risk factors of type 2 diabetes complicated with cerebral infarction. Methods A case-control study with a 1:1 ratio was used. The conditional logistic regression model was used to analyze the data. Results The degree of education is related to cerebral infarction with type 2 diabetes. After suffering from type 2 diabetes, proper physical exercise and labor intensity can reduce the risk of cerebral infarction. The higher the high-density lipoprotein (HDL C), the lower the risk of type 2 diabetes with cerebral infarction. After blood glucose control, you can also reduce the risk of type 2 diabetes with cerebral infarction. The above factors are protective factors. Excessive salt intake can increase the risk of type 2 diabetes with cerebral infarction. Snoring increases the risk of cerebral infarction in patients with type 2 diabetes. Hypertension is an independent risk factor for type 2 diabetes with cerebral infarction. Atrial fibrillation is an important risk factor for type 2 diabetes with cerebral infarction. Type A personality is associated with type 2 diabetes mellitus with cerebral infarction, showing that there are obvious personality characteristics in the occurrence of cerebral infarction in type 2 diabetes. Hyperinsulinemia is a risk factor for cerebral infarction in type 2 diabetes. Increased levels of low-density lipoprotein (LDL C), apolipoprotein a [Lp(a)], and fibrinogen (Fg) may increase the risk of type 2 diabetes with cerebral infarction. The study did not find that smoking, drinking, oral contraceptives, gestosis, total cholesterol (TC), triglycerides (TG), and Apo B were associated with cerebral infarction in type 2 diabetes. Conclusion In order to control type 2 diabetes mellitus complicated with cerebral infarction, we should promote appropriate physical exercise, eat more vegetables, control excessive salt intake, control blood sugar and blood pressure, and hyperinsulinemia.