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目的:考察盐酸胺碘酮注射液与5%葡萄糖注射液、10%葡萄糖注射液、葡萄糖氯化钠注射液及0.9%氯化钠注射液的配伍稳定性。方法:采用紫外分光光度法测定盐酸胺碘酮注射液与4种输液在室温下配伍后8 h 内不同时间的含量变化,并观察溶液外观性状及 pH 的变化。结果:盐酸胺碘酮注射液与10%葡萄糖注射液、葡萄糖氯化钠注射液及0.9%氯化钠注射液配伍后,pH 及含量均有明显变化;与5%葡萄糖注射液配伍8h 内,各项指标均无明显变化,溶液稳定。结论:盐酸胺碘酮注射液可与5%葡萄糖注射液在常温下配伍于8 h 内使用。
OBJECTIVE: To investigate the compatibility of amiodarone hydrochloride injection with 5% glucose injection, 10% glucose injection, glucose and sodium chloride injection and 0.9% sodium chloride injection. Methods: The contents of amiodarone hydrochloride injection and four kinds of infusions at different times within 8 h after compatibility were measured by UV spectrophotometry. The appearance and pH of the solution were observed. Results: Amiodarone hydrochloride injection and 10% glucose injection, glucose and sodium chloride injection and 0.9% sodium chloride injection compatibility, the pH and content were significantly changed; and 5% glucose injection compatibility 8h, No significant changes in the indicators, the solution is stable. Conclusion: Amiodarone hydrochloride injection can be used with 5% glucose injection at room temperature for 8 h.