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目的研究辽宁省彰武县农村人群的血脂浓度、血脂异常的分布及其与缺血性心脑血管疾病发生率的关系。方法采用整群随机抽样方法对2002—2005年辽宁省彰武县6个乡11个村18岁以上共5086人进行了血脂检测,并调查缺血性心脑血管疾病的患病率,分析血脂与缺血性心脑血管疾病的关系。结果无论男女,总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)浓度均随年龄增长而增加,异常率20%~30%,缺血性心脑血管疾病患病组血脂平均浓度高于非患病组(P<0.01),不同血脂分层间缺血性心脑血管疾病发生率比较差异有统计学意义(P<0.01)。结论该地区人群血脂浓度随年龄增长而逐渐增高,缺血性心脑血管疾病发生率与血脂增高密切相关。
Objective To study the distribution of plasma lipids, the distribution of dyslipidemia and the incidence of ischemic cardiovascular and cerebrovascular diseases in rural population in Zhangwu County of Liaoning Province. Methods A total of 5086 people over 11 years old in 11 villages of 6 townships in Zhangwu County of Liaoning Province from 2002 to 2005 were tested for blood lipids and the prevalence of ischemic cardiovascular and cerebrovascular diseases were investigated. And ischemic cardiovascular and cerebrovascular diseases. Results Both male and female, the levels of total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) increased with age, with an abnormality rate of 20% -30%. Ischemic cardiovascular and cerebrovascular diseases The average concentration of lipids in the diseased group was higher than that in the non-diseased group (P <0.01). There was significant difference in the incidence of ischemic cardiovascular and cerebrovascular diseases between different lipid layers (P <0.01). Conclusion The concentration of blood lipids in the population gradually increases with age. The incidence of ischemic cardiovascular and cerebrovascular diseases is closely related to the increase of blood lipids.