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目的:探讨伊曲康唑与硝酸咪康唑栓联合治疗念珠菌性阴道炎临床疗效。方法:选取2012年4月至2014年6月我院收治的念珠菌性阴道炎患者45例作为研究对象。按照随机数字表法将患者分为观察组和对照组,观察组22例,对照组23例。对照组患者采取硝酸咪康唑栓治疗。观察组患者采取伊曲康唑与硝酸咪康唑栓联合治疗。观察两组患者临床疗效,不良反应发生情况。结果:观察组患者治疗总有效率为95.45%,显著高于对照组的78.26%,两组比较,差异具有统计学意义(P<0.05)。观察组患者不良反应发生率为13.64%,对照组为17.39%,两组比较,差异无统计学意义(P>0.05)。结论:伊曲康唑与硝酸咪康唑栓联合治疗念珠菌性阴道炎疗效佳,值得临床推广。
Objective: To investigate the clinical efficacy of itraconazole and miconazole nitrate suppository in the treatment of Candida vaginitis. Methods: Forty-five patients with candida vaginitis admitted from April 2012 to June 2014 in our hospital were selected as the research object. The patients were divided into observation group and control group according to random number table method, 22 cases in observation group and 23 cases in control group. Control group patients treated with miconazole nitrate suppository. Patients in the observation group were treated with itraconazole and miconazole nitrate suppositories. The clinical efficacy and adverse reactions of the two groups were observed. Results: The total effective rate of observation group was 95.45%, which was significantly higher than that of control group (78.26%). The difference between the two groups was statistically significant (P <0.05). In the observation group, the incidence of adverse reactions was 13.64% in the control group and 17.39% in the control group. There was no significant difference between the two groups (P> 0.05). Conclusion: The combination of itraconazole and miconazole nitrate suppository for the treatment of Candida vaginitis is worthy of clinical promotion.