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利什曼原虫病是一种由利什曼原虫引起的传染性寄生虫病,广泛分布于全世界的热带和亚热带地区,影响数百万人的健康。近年来利什曼原虫病有增加趋势。它可分为三个类型:即皮肤型,皮肤黏膜型和内脏型。只有皮肤型能自愈,其他两型的自然感染过程导致严重的后果。该病痊愈后能产生稳固的免疫力,为用疫苗防治利什曼原虫病提供了前提条件。本文陈述了各类利什曼原虫疫苗的研究过程和成果以及存在的问题。
Leishmaniasis is a parasitic infectious parasitic disease caused by Leishmania, widely distributed in the tropical and subtropical regions of the world, affecting the health of millions of people. Leishmaniasis has shown an increasing trend in recent years. It can be divided into three types: the skin type, mucocutaneous and visceral type. Only the skin type can be self-healing, the other two types of natural infection process has serious consequences. After the disease is cured can produce a solid immunity, for the prevention and treatment of leishmaniasis vaccine provides the prerequisite. This article describes the research progress and achievements of various Leishmania vaccines and their existing problems.