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目的:研究妊娠高血压患者血清瘦素、胱抑素C(Cys C)以及人绒毛膜促性腺激素(β-HCG)水平检测的临床意义。方法:选取2014年4月到2015年4月我院收治的妊娠高血压患者90例(妊娠高血压组),另选同期正常妊娠者90例(正常妊娠组),健康体检非妊娠妇女90例(对照组),测量三组血清瘦素、Cys C以及β-HCG水平,并分析各指标的相关性。结果:妊娠高血压组和正常妊娠组血清瘦素、Cys C以及β-HCG水平均显著高于对照组,比较差异具有统计学意义(P<0.05),妊娠高血压组血清瘦素、Cys C以及β-HCG水平均显著高于正常妊娠组,比较差异具有统计学意义(P<0.05);妊娠高血压越严重血清瘦素、Cys C以及β-HCG水平越高;妊娠高血压患者血清瘦素与Cys C和β-HCG均呈正相关关系(P<0.05),Cys C与β-HCG也呈正相关关系(P<0.05)。结论:检测血清中瘦素、Cys C和β-HCG水平有利于妊娠高血压的诊断,体检时发现上述物质异常升高要高度重视。
Objective: To study the clinical significance of serum leptin, cystatin C (Cys C) and human chorionic gonadotropin (β-HCG) in patients with pregnancy-induced hypertension. Methods: From April 2014 to April 2015, 90 pregnant women with pregnancy-induced hypertension (90 cases of pregnancy-induced hypertension), 90 cases of normal pregnancy (normal pregnancy group), 90 healthy non-pregnant women (Control group). The levels of serum leptin, Cys C and β-HCG in the three groups were measured, and the correlation of each index was analyzed. Results: The levels of serum leptin, Cys C and β-HCG in pregnancy-induced hypertension group and normal pregnancy group were significantly higher than those in control group (P <0.05). Serum leptin, Cys C (P <0.05). Serum levels of leptin, Cys C and β-HCG in the patients with severe pregnancy-induced hypertension were significantly higher than those in the normal pregnancy group There was a positive correlation between Cys C and β-HCG (P <0.05), Cys C and β-HCG (P <0.05). Conclusion: The detection of serum leptin, Cys C and β-HCG levels is beneficial to the diagnosis of pregnancy-induced hypertension. The physical abnormalities of these substances should be paid more attention.