生理上,一氧化氮由内皮型和神经元型一氧化氮合酶(neuronal nitric oxide synthase,nNOS)生成。nNOS虽首先在大脑中被识别,但它也在其他组织,包括心脏和骨骼肌中表达。越来越多的实验证据表明,nNOS对心血管功能有重要的影响,但其对人类全身血液动力学的综合影响仍未知。研究人员进行了第一 Physiologically, nitric oxide is produced by endothelial and neuronal nitric oxide synthase (nNOS). Although nNOS is first recognized in the brain, it is also expressed in other tissues, including heart and skeletal muscle. More and more experimental evidence shows that nNOS has an important effect on cardiovascular function, but its combined effect on human whole body hemodynamics is still unknown. Researchers conducted the first