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目的探讨少量尿促性腺激素(HMG)促排卵周期的子宫内膜准备方案对冷冻胚胎移植的临床结局影响。方法回顾性分析,既往排卵正常,根据内膜准备的方法,分自然周期(A组274人)和少量HMG促排方案(B组176人)。人工周期(C组100)主要用于月经不规则者。比较3组患者的年龄、子宫内膜厚度、临床妊娠率、流产率等。结果患者的年龄、子宫内膜厚度、移植优质胚胎率,差异均无统计学意义,3组临床妊娠率分别为45.3%、54.5%,35.0%,其中B组妊娠率最高,B组与C组相比差别具有统计学意义P<0.05,A组与B组和C组相比,差别无统计员意义P>0.05,3组流产率、异位妊娠率均无明显差别。结论在冷冻胚胎移植周期,月经周期规则采用少量HMG促排周期的子宫内膜准备方案,获得较好的临床妊娠率。
Objective To investigate the effect of a small amount of urinary gonadotropin (HMG) on ovulation cycle in endometrial preparation on the outcome of frozen embryo transfer. Methods Retrospective analysis, previous normal ovulation, according to the method of intimal preparation, divided into natural cycles (A group of 274 people) and a small amount of HMG promoting program (B group of 176 people). The artificial cycle (C group 100) is mainly used for irregular menstruation. The age, endometrial thickness, clinical pregnancy rate and miscarriage rate of the three groups were compared. Results The patient’s age, endometrial thickness and the rate of high-quality embryo transfer did not reach statistical significance. The clinical pregnancy rates in the three groups were 45.3%, 54.5% and 35.0%, respectively. The pregnancy rate in group B was the highest, while in group B and C Compared with the difference was statistically significant P <0.05, A group and B group and C group, the difference was no statistical significance P> 0.05, group 3 miscarriage rate, ectopic pregnancy rate no significant difference. Conclusion During the period of frozen embryo transfer, the menstrual cycle rule adopts a small amount of endometrial preparation program with HMG promoting cycle to obtain better clinical pregnancy rate.