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目的探讨依达拉奉联合氯吡格雷治疗急性脑梗死的治疗效果及应用价值。方法选择急性脑梗死患者98例采用随机数字表法均分为观察组和对照组(n=49),对照组给予氯吡格雷治疗,观察组给予氯吡格雷联合依达拉奉治疗,观察2组治疗情况。结果观察组治疗总有效率为95.02%,对照组治疗总有效率为77.55%,组间对比差异有统计学意义(P<0.05)。观察组治疗后神经功能缺损评分(7.31±1.39)、日常生活能力评分(76.94±8.15),对照组治疗后神经功能缺损评分(13.66±2.94)、日常生活能力评分(60.47±6.03),组间对比差异有统计学意义(P<0.05)。结论采用依达拉奉联合氯吡格雷治疗急性脑梗死临床疗效优于单纯应用氯吡格雷治疗,可以有效改善患者神经功能缺损症状,提高患者日常生活能力,值得在临床上大力推广使用。
Objective To investigate the therapeutic effect and application value of edaravone and clopidogrel in the treatment of acute cerebral infarction. Methods A total of 98 patients with acute cerebral infarction were randomly divided into observation group (n = 49) and control group (n = 49). The control group was treated with clopidogrel. The observation group was given clopidogrel plus edaravone. The observation group 2 Group treatment. Results The total effective rate of the observation group was 95.02%, while that of the control group was 77.55%. The difference between the two groups was statistically significant (P <0.05). After treatment, the neurological deficit score (7.31 ± 1.39), daily living ability score (76.94 ± 8.15), neurological deficit score (13.66 ± 2.94), daily living ability score (60.47 ± 6.03) in control group after treatment, The difference was statistically significant (P <0.05). Conclusion The clinical efficacy of edaravone combined with clopidogrel in the treatment of acute cerebral infarction is superior to that of clopidogrel alone. It can effectively improve the symptoms of patients with neurological deficits and improve the daily living ability of patients. It is worth to be used clinically.