生物芯片技术同时将大量探针固定于支持物上,可以一次性对样品大量序列进行检测和分析,根据其制备方法、在固相载体上排列的探针及检测功能的不同分为若干类型。主要用于检测肿瘤组织中基因突变和多态性分析,肿瘤的分类、诊断和鉴别诊断,癌基因、抑癌基因的功能研究,肿瘤组织基因谱的检测,化疗药物作用及耐药形成机制研究和肿瘤组织细胞周期调控机制的研究。 Biochip technology simultaneously immobilizes a large number of probes on a support, and can detect and analyze a large number of samples at a time. According to the preparation method, probes arrayed on a solid support and detection functions are classified into several types. It is mainly used to detect gene mutation and polymorphism in tumor tissues, classification, diagnosis and differential diagnosis of tumor, function of oncogenes and tumor suppressor genes, detection of tumor gene profile, chemotherapeutic effects and mechanism of drug resistance And tumor cell cycle regulation mechanism.