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老年人因组织器官衰老,对药物的吸收、代谢、排泄的功能降低,药物不良反应的发生率也显著增高,因此必须重视老年人的合理用药,以减少不良反应的发生。1心血管系统药物1.1乙胺碘呋酮此药可抑制窦房结和心脏的传导系统功能,发生窦性心动过缓、窦房结传导阻滞或各种房室传导阻滞,这种不良反应老年人最易发生,其中窦性心动过缓及Ⅰ度、Ⅱ度房室传导阻滞最为常见且不被阿托品所拮抗,因此窦
Due to the aging of tissues and organs, the elderly have lower functions of absorption, metabolism and excretion of drugs, and the incidence of adverse drug reactions is also significantly increased. Therefore, rational use of drugs in the elderly must be emphasized to reduce the occurrence of adverse reactions. 1 cardiovascular system drugs 1.1 amiodarone This medicine can inhibit the sinus node and heart conduction system function, sinus bradycardia occurred, sinus node conduction block or atrioventricular block, this bad Response to the elderly most likely to occur, including sinus bradycardia and Ⅰ degree, Ⅱ degree atrioventricular block is the most common and not antagonized by atropine, sinus