微小RNA(mi RNA)通过与对应的靶基因结合,调控生物体的生殖、发育等生命活动。mi R-518b是一种胎盘特异性mi RNA,与子痫前期、完全性葡萄胎等不良妊娠结局发病有着密切的关系。mi R-518b可以在孕妇外周血中检测出,血清的检测可以为不良妊娠结局的诊断、监测与预防提供了新的方法,mi R-518b的相关研究为不良妊娠结局的发病机理提供了新的研究思路。 MicroRNAs (miRNAs) regulate biological activities such as reproduction and development by binding to corresponding target genes. mi R-518b is a placental-specific miRNA that is closely related to the incidence of adverse pregnancy outcomes such as preeclampsia and complete hydatidiform mole. mi R-518b can be detected in the peripheral blood of pregnant women, serum testing can provide a new method for the diagnosis, monitoring and prevention of adverse pregnancy outcomes. The related research of mi R-518b provides a new mechanism for the pathogenesis of adverse pregnancy outcomes Research ideas.