论文部分内容阅读
目的观察纳洛酮并胞二磷胆碱治疗肺性脑病的疗效。方法将42例肺性脑病患者随机分为治疗组和对照组。两组观察时限以24h为标准。治疗组给予纳洛酮0·8mg~1·2mg加入500ml液体中维持静脉滴注,胞二磷胆碱0·5g加入500ml液体中维持静脉滴注。对照组给予尼可刹米1·500~1·875g+洛贝林15mg加入500ml液体中维持静脉滴注。结果治疗组有效率达86·0%,对照组为50·0%,经统计学处理,两组比较差异有统计学意义(χ2=4·346,P<0·05)。治疗组意识转变为清楚的时间平均12·4h,对照组为33·1h,两组比较差异有统计学意义(t=8·325,P<0·01)。结论纳洛酮并胞二磷胆碱治疗肺性脑病疗效高、安全,值得临床推广使用。
Objective To observe the curative effect of naloxone and citicoline on pulmonary encephalopathy. Methods 42 cases of pulmonary encephalopathy were randomly divided into treatment group and control group. Two groups of observation time to 24h as the standard. The treatment group was given naloxone 0 · 8mg ~ 1 · 2mg added 500ml liquid to maintain intravenous drip, Citicoline 0.5g added to 500ml of liquid to maintain intravenous drip. The control group was given Nicotine 1 · 500 ~ 1 · 875g + Lobeline 15mg added 500ml liquid to maintain intravenous drip. Results The effective rate was 86.0% in the treatment group and 50.0% in the control group. The difference was statistically significant (χ2 = 4.46, P <0.05). The treatment group consciousness was changed to a clear time average of 12.4h, the control group was 33.1h, the difference between the two groups was statistically significant (t = 8 · 325, P <0.01). Conclusion Naloxone and citicoline treatment of pulmonary encephalopathy with high efficacy and safety, worthy of clinical promotion and use.