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目的探讨静滴α-细辛脑与氨茶碱治疗婴幼儿喘憋性肺炎临床疗效及不良反应。方法选取2009年1月份到2010年1月份来我院治疗被诊断为喘憋性肺炎的婴幼儿80例,随机分为对照组和观察组,对照组45名,观察组35名,对照组使用氨茶碱静脉点滴,观察组采用α-细辛脑静脉点滴,观察两组的咳嗽、肺部湿罗音以及其他临床症状来衡量药物治疗的有效性,并观察两组患者药物治疗的不良反应表现。结果经过治疗后,两组患者的临床表现均有所减轻,观察组的总有效率为91.43%,对照组的总有效率为82.2%,观察组的治疗效果比对照组的明显,而观察组的药物不良反应情况比对照组少而轻,两组比较差异具有统计学意义(P<0.05)。结论在治疗婴幼儿喘憋性肺炎中,α-细辛脑具有明显的止咳、祛痰、平喘、镇静、解痉等作用,而且副作用少,价格便宜,值得临床广泛推广。
Objective To investigate the clinical efficacy and adverse reactions of intravenous α-asarone and aminophylline in the treatment of infantile asthmatic pneumonia. Methods 80 cases of infants and young children diagnosed as wheezing pneumonia were treated in our hospital from January 2009 to January 2010. They were randomly divided into control group and observation group, 45 in control group, 35 in observation group and 35 in control group Aminophylline intravenous drip, the observation group using α-asarone intravenous drip to observe the two groups of cough, pulmonary rales and other clinical symptoms to measure the effectiveness of drug treatment, and to observe the two groups of patients with adverse drug reactions which performed. Results After treatment, the clinical manifestations of both groups were alleviated. The total effective rate was 91.43% in the observation group and 82.2% in the control group. The treatment effect in the observation group was more obvious than that in the control group. The observation group The adverse reactions of the drugs were less and lighter than that of the control group, and the differences between the two groups were statistically significant (P <0.05). Conclusion In the treatment of infantile asthmatic pneumonia, α-Asarone has obvious antitussive, expectorant, antiasthmatic, sedative, antispasmodic and other effects, and less side effects, the price is cheap, it is worth widely clinical promotion.