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摘译:在人类不同组织类型癌症发生率变化很大,这一现象已经被发现长达一个世纪,但是始终无法解释。我们发现在正常细胞自我更新过程中,干细胞分裂次数在不同的组织中是不同的,干细胞分裂次数越多的组织,癌症发病率越高,两者的相关系数高达0.804。在正常组织干细胞发生分裂时,DNA复制
Excerpt: The incidence of cancer in different types of human tissues has changed dramatically, a phenomenon that has been discovered for centuries but never explained. We found that in the process of normal cell self-renewal, the number of stem cell divisions is different in different tissues. The more the number of stem cell divisions, the higher the incidence of cancer, and the correlation coefficient is as high as 0.804. DNA replication occurs when normal tissue stem cells divide