论文部分内容阅读
目的:观察长期经皮神经肌肉低频电刺激结合糖尿病减肥康复教育对2型糖尿病(T2DM)患者代谢指标的影响,为探索治疗T2DM的方法提供实验依据。方法:选取符合诊断标准的T2DM伴腹型肥胖患者50人,随机分为实验组和对照组各25人。实验组每天进行30 min腹部经皮神经肌肉低频电刺激治疗,频率30 Hz,波宽为300μs,通断比为2秒:6秒,电流强度为10~20 mA,每天1次,持续12周。实验组和对照组每周均进行糖尿病人减肥康复教育1次。12周前后分别测试身体形态、糖脂代谢指标,进行比较分析。结果:①与对照组相比,实验后实验组体重、体重指数、腰围和臀围显著降低(P<0.05);血清总胆固醇、低密度脂蛋白、糖化血红蛋白、甘油三酯、血糖水平下降显著(P<0.05),高密度脂蛋白变化不明显(P>0.05),血清游离脂肪酸、胰岛素、瘦素、内脏脂肪素水平和胰岛素抵抗指数显著降低(P<0.05)。②与实验前比较,实验后实验组血清血糖、糖化血红蛋白、甘油三酯、游离脂肪酸、胰岛素、瘦素、内脏脂肪素水平和胰岛素抵抗指数均显著性降低(P<0.01,P<0.001)。结论:长期神经肌肉电刺激结合糖尿病减肥康复教育有效辅助腹型肥胖T2DM患者控制代谢风险.正性调节血糖、血脂,减轻胰岛素抵抗,效果明显优于单纯糖尿病减肥康复教育。
OBJECTIVE: To observe the effect of long-term percutaneous neuromuscular low-frequency electrical stimulation combined with diabetes and weight loss rehabilitation education on metabolic indices in patients with type 2 diabetes mellitus (T2DM), and to provide experimental evidence for exploring methods of treating T2DM. Methods: 50 T2DM patients with abdominal obesity who meet the diagnostic criteria were randomly divided into experimental group and control group with 25 in each. The experimental group was treated with low-frequency electric stimulation of abdominal percutaneous neuromuscular stimulation for 30 min every day, the frequency was 30 Hz, the wave width was 300 μs, the on-off ratio was 2 seconds: 6 seconds, the current intensity was 10-20 mA, once daily for 12 weeks . The experimental group and control group were once weekly diabetic weight loss rehabilitation education 1. Body shape and glucose and lipid metabolism indexes were tested before and 12 weeks later for comparative analysis. Results: ①Compared with the control group, the body weight, body mass index, waist circumference and hip circumference of the experimental group decreased significantly (P <0.05); the levels of serum total cholesterol, LDL, HbAlc, triglyceride and blood glucose decreased significantly (P <0.05), while HDL did not change significantly (P> 0.05). Serum levels of free fatty acids, insulin, leptin, visceral adiponectin and insulin resistance were significantly decreased (P <0.05). ② Compared with the pre-experiment, the levels of serum glucose, glycosylated hemoglobin, triglyceride, free fatty acid, insulin, leptin, visfatin and insulin resistance index in experimental group were significantly decreased (P <0.01, P <0.001). CONCLUSION: Long-term neuromuscular stimulation combined with diabetes diet and rehabilitation education can effectively control the metabolic risk of T2DM patients with abdominal obesity, and positively regulate blood sugar, blood lipid and insulin resistance, which is obviously better than simple diabetes mellitus rehabilitation education.