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The synthesis of racemic cedarmycin B,an antibiotic from Streptomyces sp.TP-A0456 was achieved firstly from γ-butyrolactone.The key step was a Barbier-type addition of 3-bromomethyl-5H-furan-2-one to formaldehyde mediated by zinc,which afforded the sole 7-addition product 4-hydroxymethyl-3-methylene-dihydrofuran-2-one.The final compound was confirmed by 1H NMR,13C NMR and HRMS.