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目的:研究并分析治疗过期流产患者时使用米非司酮的治疗效果。方法:收集过期流产患者共98例,根据患者入院日期的单双号数分为49例对照组和49例观察组,所有患者接受清宫术治疗,对照组患者在手术前服用己烯雌酚,观察组在手术前服用米非司酮,将两组患者的胚胎娩出时间、术中出血量、宫口松弛度合适例数以及二次清宫患者例数进行观察和对比。结果:观察组患者的胚胎娩出时间为(2.0±0.6)h,明显短于对照组的(5.1±1.2)h,观察组患者的术中出血量为(64.9±15.2)ml,显著低于对照组患者的(86.4±15.5)ml,观察组宫口松弛度适合例数比例为95.9%,显著高于对照组的61.2%,观察组二次清宫发生率为14.3%,显著少于对照组的(36.7%,P均<0.05)。结论:在过期流产患者的治疗过程中,使用米非司酮能够提高患者宫口的松弛度,促进胚胎的脱落,降低患者需要接受二次清宫的风险,减轻患者负担,值得推广应用。
OBJECTIVE: To study and analyze the effect of mifepristone in the treatment of patients with abortion. Methods: A total of 98 patients with overdue abortion were collected. Based on the single and double numbers of admission date, 49 patients were divided into 49 control groups and 49 observation groups. All patients underwent radical mastectomy. Patients in the control group received diethylstilbestrol before operation. Mifepristone before surgery, the two groups of patients with embryo delivery time, intraoperative blood loss, appropriate number of cervix laxity and the number of patients with secondary clearance were observed and compared. Results: The time of embryo delivery in the observation group was (2.0 ± 0.6) h, which was significantly shorter than that in the control group (5.1 ± 1.2) h. The intraoperative blood loss in the observation group was (64.9 ± 15.2) ml, significantly lower than that of the control (86.4 ± 15.5) ml in the group and 95.9% in the observation group (95.9%) were significantly lower than that in the control group (14.3%), which was significantly lower than that in the control group (36.7%, P <0.05). Conclusion: Mifepristone can increase the lavage of cervix, promote the shedding of embryos, reduce the risk of second recidivism and reduce the burden of patients during the treatment of patients with expiratory abortion, which is worth popularizing and applying.